Is MOTS-c legal?
Medically reviewed by Dr. Jonathan Snipes, MD
Reviewed for clinical accuracy · Last reviewed July 22, 2026 · Review policy
Quick answer
MOTS-c is not FDA-approved, is prohibited in sport, and its compounding pathway was under FDA review at the July 2026 PCAC meeting.
- FDA status
- Not FDA-approved; compounding under FDA review (July 2026)
- Prohibited in sport (WADA)
- Yes
MOTS-c is not an FDA-approved drug and is prohibited in sport under the WADA framework. It has been available through compounding and the research-chemical market. It was one of the seven peptides the FDA's Pharmacy Compounding Advisory Committee reviewed on July 23, 2026, for the 503A Bulks List, with briefing documents recommending against listing. The vote is advisory and the FDA decides separately.
Frequently asked questions
Is MOTS-c legal in the US?+
MOTS-c is not FDA-approved, is prohibited in sport, and its compounding pathway was under FDA review at the July 2026 PCAC meeting.
Do you need a prescription for MOTS-c?+
MOTS-c is not FDA-approved. Where it is available through a compounding pharmacy it requires a prescription; research-chemical versions are sold outside the regulated, prescription-based system.