Weight Loss & GLP-1
The Best GLP-1 Weight Loss Programs of 2026
We tested the leading online GLP-1 weight loss programs on price, medication access, clinician quality and support. Here are the providers worth your money.
Quick answer
Ro (4.4/5) is our top-rated weight loss provider, best overall, starting at $149/mo + medication. Sesame (4.4/5) is our Best Value pick.
GLP-1 medications like semaglutide and tirzepatide have reshaped medical weight loss, and a wave of telehealth programs now make them accessible without an in-person clinic. But programs differ enormously on price, what medication they can actually prescribe, and how much human support you get. We evaluated the leading options so you can pick the right one.
Our editors assessed each program on four weighted criteria: total monthly cost, medication access and continuity, clinician quality, and ongoing coaching and support. None of the rankings below are paid placements. See our methodology for exactly how we score.
Pick by what matters to you
The right choice depends on your priority. Here is the standout for each.
Our top pick overall, 4.4/5 on the rubric.
Lowest PriceBest value for the money, from $39 visit + pharmacy cost.
Most ClinicalStrong clinical quality, 4.6/5.
Best for Multiple ProductsOne provider for several needs, not just this one.
At a glance
| # | Service | Best for | Rating | From | Link |
|---|---|---|---|---|---|
| 1 | Ro | Best Overall | ★★★★★4.4 | $149/mo + medication | Visit |
| 2 | Sesame | Best Value | ★★★★★4.4 | $32/visit | Visit |
| 3 | RxPepsDirect | Best for Compounded GLP-1 | ★★★★★4.4 | $39 visit + pharmacy cost | Visit |
| 4 | Found | Best for Coaching | ★★★★★4.1 | $99/mo | Visit |
| 5 | Hims & Hers | Best All-in-One App | ★★★★★4.1 | $79/mo | Visit |
Ro
Full-service telehealth with in-house pharmacy
Pros
- ✓Best route to brand-name (non-compounded) GLP-1s
- ✓Free insurance check plus prior-authorization advocacy
- ✓Includes coaching and an in-house pharmacy
Cons
- ✕Care is async-primary, not everyone gets a live video visit
- ✕Layered cost: roughly $298/mo cash before insurance (membership plus medication)
Our verdict: The pick for brand-name GLP-1s with real insurance and prior-authorization support, if you are comfortable with mostly async care and a layered membership-plus-medication cost.
Visit Ro →Sesame
Cash-pay marketplace, no membership
Pros
- ✓No subscription
- ✓Upfront cash prices
- ✓Wide visit catalog
Cons
- ✕No insurance billing
- ✕Quality varies by clinician
Our verdict: The value pick when you want a one-off visit, not a membership.
Visit Sesame →RxPepsDirectAffiliated
Prescription peptides at pharmacy pricing
Pros
- ✓Flat $39 visit fee with no subscription
- ✓Pharmacy bills medication at wholesale, no markup
- ✓Medical director and NP-led prescribing
- ✓Broad non-controlled peptide menu
Cons
- ✕Cash-pay only, no insurance
- ✕Medication billed separately by the pharmacy
- ✕Available in 28 states plus DC
- ✕Limited third-party review volume so far
Our verdict: A transparent, pharmacy-priced route to clinician-prescribed compounded peptides.
Visit RxPepsDirect →Found
Weight care with behavioral coaching
Pros
- ✓Coaching + medication
- ✓Personalized plans
- ✓Good app habit tracking
Cons
- ✕Medication priced separately
- ✕Waitlists at times
Our verdict: Best for people who want coaching alongside a GLP-1.
Visit Found →Hims & Hers
Mass-market telehealth across many categories
Pros
- ✓Broad category coverage
- ✓Sleek app
- ✓Frequent promos
Cons
- ✕Upsell-heavy flow
- ✕Variable provider response times
Our verdict: Best for shoppers who want one app for many needs.
Visit Hims & Hers →How we chose the best GLP-1 programs
We prioritized programs that pair an actual prescribing clinician with transparent, all-in pricing, not just a coaching app or a medication storefront. We also weighted continuity of care, because GLP-1 treatment is a months-long journey where dose titration and side-effect management matter.
What to look for in a GLP-1 program
- Transparent pricing that includes the consultation, not just the medication
- Clear policy on brand-name vs. compounded medication
- Access to a clinician for dose adjustments and side effects
- No long lock-in contracts or surprise renewal charges
A program that looks cheap up front can cost more once medication, labs and follow-ups are added. When you compare, always price the full first three months.
The bottom line
For most people, Ro offers the most complete experience thanks to its integrated pharmacy and strong clinician support. If behavioral coaching matters more to you than convenience, Found is the better fit, and Sesame is the value pick for anyone who wants to avoid a membership.
Frequently asked questions
Are online GLP-1 weight loss programs legitimate?+
Reputable programs connect you with licensed clinicians who evaluate your eligibility before prescribing. Always confirm the program uses U.S.-licensed providers and a verified pharmacy, and discuss any treatment with your own doctor.
How much do GLP-1 programs cost without insurance?+
Total monthly cost typically ranges from roughly $99 to $400+ depending on whether the program uses brand-name or compounded medication and what support is bundled in. Always price the full first three months including consults and labs.
Do these programs take insurance?+
Most direct-to-consumer GLP-1 programs are cash-pay, though some can provide documentation to submit to your insurer. Coverage for weight-loss GLP-1s remains limited and varies widely by plan.