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Sexual Health

The Best At-Home STD Tests of 2026

We compared the leading at-home STD tests on accuracy, which infections they cover, result speed, privacy, and whether treatment is included. Here are the best.

The TeleRanked Editors·Reviewed by our clinical advisory team·Updated July 24, 2026·9 min read

Quick answer

LetsGetChecked (4.4/5) is our top-rated sexual health provider, best overall, starting at $89 per test. Everlywell (3.6/5) is our Best for Test Variety pick.

Editorially independent: Our rankings and ratings are decided by our editors and are never for sale. Clinics can claim and manage their profile, but cannot pay to change their position or score. See our methodology.

At-home STD testing lets you collect a sample in private, mail it to a certified lab, and get results online, often with a clinician to prescribe treatment if anything comes back positive. The services differ on which infections they screen for, how the sample is collected, how fast results arrive, and whether treatment is bundled in or a separate step.

We evaluated each option on lab accreditation, panel coverage, result speed, privacy, and access to treatment. None of the rankings below are paid placements.

Pick by what matters to you

The right choice depends on your priority. Here is the standout for each.

At a glance

#ServiceBest forRatingFromLink
1LetsGetCheckedBest Overall★★★★★4.4$89 per testVisit
2EverlywellBest for Test Variety★★★★★3.6$49 per testVisit
3myLAB BoxBest for the Widest Panel★★★★★3.6$59 single testVisit
4WispBest for Same-Day Treatment★★★★★4.0$39 STI consultVisit
1
Best Overall

LetsGetChecked

At-home kits with telehealth follow-up

★★★★★4.4STI kits from $99

Pros

  • Strong Trustpilot rating across 17,000-plus reviews
  • Telehealth consults and prescriptions via affiliate pharmacy
  • Replies to most negative reviews within 24 hours

Cons

  • Complaints about blood-sample volume and result delays
  • BBB reports of expired kits and refund trouble
  • Support sometimes found unhelpful

Our verdict: Well-rated at-home testing with integrated telehealth support.

Visit LetsGetChecked
2
Best for Test Variety

Everlywell

Mail-in test kits for many conditions

★★★★★3.6Rapid HIV $49, lab tests from $69

Pros

  • 30-plus kits covering a wide range of needs
  • CLIA-certified, CAP-accredited lab with physician-reviewed results
  • HSA and FSA payments accepted

Cons

  • Frequent finger-prick sample rejection and invalid results
  • Delayed shipping pushes past result windows
  • Poor refund and support responsiveness; low BBB rating

Our verdict: Convenient mail-in kits, but collection and support issues recur.

Visit Everlywell
3
Best for the Widest Panel

myLAB Box

At-home STI and wellness test kits

★★★★★3.65-panel $179, 14-panel to $409

Pros

  • Wide at-home STI panel selection, single tests up to 14-panel
  • Free physician consult if a result is positive
  • Sold direct plus via Amazon, Target, Walmart

Cons

  • Shipping and sample-tracking delays reported
  • Slow or unhelpful customer service for some
  • Occasional false-positive and accuracy complaints

Our verdict: Comprehensive at-home STI testing, let down by shipping and support.

Visit myLAB Box
4
Best for Same-Day Treatment

Wisp

Fast online sexual and reproductive care

★★★★★4.0$39 consult, kits from $99

Pros

  • Fast prescriptions sent same day to local pharmacy
  • Discreet cash-pay model, no insurance hassle
  • Large established platform serving millions of patients

Cons

  • Reports of charges for declined or unfilled services
  • Actual turnaround sometimes slower than advertised
  • Customer service response can lag on billing issues

Our verdict: Convenient, affordable cash-pay sexual and reproductive care.

Visit Wisp

How we ranked at-home STD tests

We favored tests processed by CLIA-certified labs, with clear panels that cover the common infections, fast and private results, and a path to treatment when a result is positive. We noted which services include a clinician consult and prescription, because a test alone does not treat anything.

What the panels actually cover

A basic panel usually screens for chlamydia and gonorrhea, while comprehensive panels add HIV, syphilis, trichomoniasis, hepatitis, and sometimes herpes. Match the panel to your exposure and history, and remember that testing windows matter: some infections are not detectable for days to weeks after exposure.

What to look for

  • A CLIA-certified lab processing the sample
  • A panel that matches your exposure, not just chlamydia and gonorrhea
  • Fast, private results you can access online
  • A clinician who can prescribe treatment if you test positive
  • Discreet packaging and clear data-privacy terms

The bottom line

LetsGetChecked is the most trusted at-home option and our overall pick, with Everlywell the best for test variety and myLAB Box the widest panel (up to 14 infections). Where they differ most is treatment: myLAB Box includes a free telemedicine consult on a positive result and can prescribe for chlamydia, gonorrhea and trichomoniasis, and Wisp writes same-day prescriptions, while LetsGetChecked and Everlywell handle a positive result as a separate paid consult. Note that gonorrhea and syphilis usually need an in-person injection, and LetsGetChecked kits are not sold in New York.

Frequently asked questions

Are at-home STD tests accurate?+

When processed by a CLIA-certified lab and collected correctly, at-home STD tests are highly accurate. The main risks are collecting the sample improperly or testing too soon after exposure, before an infection is detectable, so follow the instructions and testing-window guidance closely.

How much does an at-home STD test cost?+

A single-infection test often runs about $30 to $70, while comprehensive panels covering HIV, syphilis, and more typically cost $100 to $200. Some services bundle a clinician consult and treatment; confirm whether that is included or an added fee.

Do at-home STD tests include treatment?+

Some do. myLAB Box includes a free telemedicine consult on a positive result and can e-prescribe oral treatment for chlamydia, gonorrhea and trichomoniasis, and Wisp writes same-day prescriptions. LetsGetChecked and Everlywell offer a clinician consult on a positive result as a separate paid step (about $39 and $79), with medication billed separately. Gonorrhea and syphilis usually require an in-person injection regardless of the provider.